The present work deals with development and validation of two precise and accurate spectrophotometric methods for the estimation of flunarizine dihydrochloride in bulk and tablet dosage form. Method A is the absorbance maxima method where absorbance maxima of the drug were recorded at 252 nm. Method B is area under the curve in which wavelength range 244-252 nm was selected for estimation of flunarizine dihydrochloride by using co-solvent method (methanol: water 50:50% v/v). Linearity was observed in the concentration range 4-24 µg/ml for both the methods (r2 = 0.999 for method A and r2 = 0.999 for method B). The results of analysis were validated statistically, which confirmed the accuracy and reproducibility of the methods. Both the methods were found to be precise and accurate and can be employed for routine quality control analysis of flunarizine dihydrochloride in bulk as well as in its solid dosage form.
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